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Acta Pharmacologica Sinica
中国药理学报(In English) Vol.21-2000
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No.1
1. Review
Endothelium-dependent hyperpolarization of vascular smooth muscle cells.
2.Original Research
Basic fibroblast growth factor up-regulates the expression of vascular
endothelial growth factor in primary cultured rat astrocytes.
Effects of Veratrum nigrum alkaloids on central catecholaminergic neurons
of renal hypertensive rats.
Molecular modeling on human CCR5 receptors and complex with CD4 antigens
and HIV-1 envelope glycoprotein gp120.
Antagonistic action of caffeine against LY294002-induced apoptosis in
cerebellar granule neurons.
High glucose enhances H2O2-induced apoptosis in bovine aortic endothelial
cells.
Molecular modeling on solvent effect and interaction mechanism of fentanyl
analogs to μ-opioid receptor.
Cell proliferation and Ca2+-calmodulin dependent protein kinase activation
mediated by α1A- and α1B-adrenergic receptor in HEK293 cells.
Inhibitory effects of dauricine on potassium currents in guinea pig ventricular
myocytes.
Huperzine A ameliorates the impaired memory of aged rat in the Morris
water maze performance.
Effect of batroxobin against dog heart ischemia/reperfusion injury.
Protective effects of bilobalide on amyloid beta-peptide 25-35-induced
PC12 cell cytotoxicity.
Application of secondary structure prediction in antisense drug design
targeting protein kinase C-α mRNA and QSAR analysis.
Effect of metallothionein on tolerance of nitroglycerin in rats.
Antagonistic effects of 3 sesquiterpene lactones from Atractylodes macrocephala
Koidz on rat uterine contraction in vitro.
Information for authors (Ⅰ)
Regulation of Acta Pharmacologica Sinica Foundation (Ⅸ)
No.2
Nicotine and brain disorders
Bradykinin B1 receptor in isolated human umbilical vein: an experimental
model of the in vitro up-regulation process
Recent advances in GABAB receptors: from pharmacology to molecular biology
Learning deficits induced by 4 belladonna alkaloids are preferentially
attenuated by tacrine
Prostacyclin-induced relaxations of small porcine pulmonary arteries are
enhanced by the basal release of endothelium-derived nitric oxide through
an effect on cyclic GMP-inhibited-cyclic AMP phosphodiesterase
Effects of exogenous testosterone on isolated rabbit corpus cavernosum
penis
Dopamine-glutamate interaction in rat striatal slices: changes of CCDPKⅡ,
PKA, and LDH activity by receptor-mediated mechanisms
Bilobalide promotes expression of glial cell line-derived neurotrophic
factor and vascular endothelial growth factor in rat astrocytes
Corticosterone impairs cultured hippocampal neurons and facilitates Ca2+
influx through voltage-dependent Ca2+ channel
Influence of batroxobin on cerebral ischemia-reperfusion injury in gerbils
Effects of TMB-8 on constriction of pial arteries in rats
High glucose impairs endothelium-dependent relaxation in rabbit aorta
Effect of PKC-ζ mediating Ang Ⅱ－stimulated activation of CCDPK on rat
cardiac fibroblast proliferation
Anti-HIV-1 activity of trichobitacin, a novel ribosome-inactivating protein
Analysis of drug interactions in combined drug therapy by reflection method
Effect of kanglemycin C on lymphocyte proliferation induced by tetradecanoylphorbol
acetate and ionomycin
No.3
1. Review
Individual and ethnic differences in CYP2C19 activity in Chinese populations.
2. Original Research
Effects of 2-［3-estrone-N-ethyl-piperazine-methyl］tetracycline (XW630)
on osteoporosis in ovariectomized rats.
Atypical antipsychotic effects of quetiapine fumarate in animal models.
Antisense oligodeoxynucleotide inhibits vascular endothelial growth factor
in human glioma cells.
Volume- and calcium-activated chloride channels in human umbilical vein
endothelial cells.
Biphasic manner of melittin on isolated guinea pig atria.
Apoptosis induced by ceramide in hepatocellular carcinoma Bel7402 cells.
Antisense Ca+\{2+-calmodulin dependent protein kinase oligonucleotide
inhibits bFGF-induced proliferation of rat vascular smooth muscle cells.
Effects of dihydroartemisinin on fine structure of erythrocytic stages
of Plasmodium berghei ANKA strain.
ntidiabetic effect of Oenanthe javanica flavone.
Molecular mechanism of apoptosis induced by ricin in HeLa cells.
Class Ⅲ anti-arrhythmic drug E-4031 potentiates Na+Ca2+ exchange current
in rat ventricular myocytes.
Effect of 6 flavonoids on proliferation of hepatic stellate cells in vitro.
Panax notoginseng saponins attenuated cisplatin-induced nephrotoxicity.
Effects of XW630 on cell proliferation,iNOS activity, and cGMP content
in human osteoblast-like line TE85.
Nonhistone protein purified from porcine kidney acts as a suicide substrate
inhibitor on furin-like enzyme.
Urethane-induced hyperglycemia.
Clearance of increased serum advanced glycosylation end products in patients
with end stage renal disease by hemodialysis.
Effect of forskolin on acetylcholine-induced current in rat pheochromocytoma
cells.
Proceedings of Symposium on the Tenth Anniversary of Foundation of CJP/JCP
Club (10th CJP-99)
No.4
1. Review
Vulnerable substrate and multiple ion channel disorder in a diseased heart
will be new targets for antiarrhythmic therapy
2.Original Research
Alteration of basic fibroblast growth factor expression in rat during
cerebral ischemia
Inhibitory effect of 1-(2,6-dimethylphenoxy)-2-(3,4-di-meth-oxy-phenyl-ethylamino)propane
hydrochloride on inward rectifier and delayed rectifier K+ currents in
guinea pig ventricular myocytes
Determination of idebenone in plasma by HPLC/MS
Different mechanisms mediate β adrenoceptor stimulated vasorelaxation
of coronary and femoral arteries
Prevention of intima hyperplasia by mitogen-activated protein kinase antisense
oligodeoxynucleotide
Antisense IRAK-2 oligodeoxynucleotide inhibits interleukin-1-induced nuclear
factor-κ B activation in vitro
Phosphatidylinositol 3-kinase modulates IL-18-induced nuclear factor-κB
activation
High glucose inhibits expression of inducible and constitutive nitric
oxide synthase in bovine aortic endothelial cells
Behavioral characteristics of olanzapine: an atypical neuroleptic
Preparation of monoclonal antibody against human m3 receptor
Platelet-derived growth factor stimulated vascular smooth muscle cell
proliferation and its molecular mechanism
Effect of anti-digoxin antiserum on endoxin and membrane ATPase activity
in hypoxia-reoxygenation induced myocardial injury
Effects of ascorbic acid and DL-α-tocopherol on human hepatoma cell proliferation
and redifferentiation
Effects of Scutellarein on diabetic rat aorta
Protective action of piperine against experimental gastric ulcer
Protective effects of fructose-1,6-diphosphate against cerebral injury
induced by subacute carbon monoxide intoxication in mice
Differentiation-inducing action of 10-hydroxycamptothecin on human hepatoma
Hep G2 cells
Effect of nitric oxide on electric and mechanical activities of gastric
antral circular muscles in guinea pigs
Blocking effects of heteroclitin D and gomisin J on L-type calcium channels
in ventricular cells of guinea pig
Cholecystokinin analog JMV-180-induced intracellular calcium oscillations
are mediated by inositol 1,4,5-trisphosphate in rat pancreatic acini
Effects of angiotensin-converting enzyme and angiotensin Ⅱ on hypoxia-induced
proliferation of cultured intra-pulmonary artery smooth muscle cells
No.5
1. Review
Potential mechanisms for cardiovascular protective effect of ethanol
Colorectal cancer and non-steroidal anti-inflammatory drugs
Ras farnesyltransferase inhibition: a novel and safe approach for cancer
chemotherapy
2.Original Research
Antagonism of LPS and IFN-γ induced iNOS expression in human atrial endothelia
by morphine,anandamide,and estrogen
Indirect neurotropic effect of neuropeptide ZNC(C)PR on PC12 cells via
peptide-stimulation of C6 cells
Protective effect of bilobalide against nitric oxide-induced neurotoxicity
in PC12 cells
Effect of melatonin on pro-opiomelanocortin mRNA expression in arcuate
nucleus of rat hypothalamus
A transient increase in CCK mRNA levels in hippocampus following audiogenic
convulsions in audiogenic seizure-prone rats
Long-term potentiation induced by nicotine in the CA1 region of hippocampal
slice is Ca2+-dependent
Inhibitory effects of chiral 3-n-butylphthalide on inflammation following
focal ischemic brain injury in rats
Arcuate nucleus of hypothalamus involved in analgesic action of l-THP
Dimethylamiloride-induced differentiation of HL-60 cells
Anti-hepatoma activity of taxol in vitro
Ebselen protection against hydrogen peroxide-induced cytotoxicity and
DNA damage in HL-60 cells
Antagonistic effect of 3,6-dimethamidodibenzopyriodonium gluconate on
lipid peroxidation in cerebral cortical neuronal cultures and rat brains
during focal cerebral ischemia reperfusion
Salvianolic acid B protects brain against injuries caused by ischemia-reperfusion
in rats
Intermittent hypoxia exposure-induced heat-shock protein 70 expression
increases resistance of rat heart to ischemic injury
Effect of lipanthyl on mRNA expression of endothelin-1 and nitric-oxide
synthase in atherosclerotic vessel wall in rabbits
Tetrahydroprotoberberines inhibit lipid peroxidation and scavenge hydroxyl
free radicals
No.6
1.Review
Role of amygdala norepinephrine in mediating stress hormone regu-lation
of memory storage
2.Original Research
Genetic polymorphism of CYP2D6 in Karnataka and AndhraPradesh population
in India
Endothelin-1 pathway in human alveolar epithelial cell line A549and human
umbilical vein endothelial cells
Patch clamp studies of motor neurons in spinal cord slices: a toolfor
high-resolution analysis of drug actions
Nociceptin, endomorphin-1 and -2 do not interact with invertebrate immune
and neural μ3 opiate receptor
Building three-dimensional structures of HIV-1 coreceptor CCR5 and its
interaction with antagonist TAK779 by comparative molecular modeling
Comparative molecular modeling on 3D-structure of opioidreceptor-like
1 receptor
Study on mechanism of interaction of nociceptin and opioids binding with
opioid receptor-like 1 receptor
Interaction between human interleukin-16 and CD4 receptorof HIV- 1
Effects of cyclophosphamide on protein expression of rat embryo at end
of pre-gastrulation stage in vivo
Amyloid-β 25- 35 peptide induces expression of monoamineoxidase B in cultured
rat astrocytes
Determination of procaterol in human plasma by gas chromatography/electron
impact ionization mass spectrometry
Comparison of effects of CH50 on macrophage activation and its an-ti-tumor
activity with those of lipopolysaccharides
Effects of nitroprusside, 3-morpholino-sydnonimine, and spermineon calcium-sensitive
potassium currents in gastric antral circular myocytes of guinea pig
No.7
1. Review
Functional implications of sole and selective activation of intravascular
coronary endothelial hormonal receptors1
Contribution of genetic variations in estradiol biosynthesis and metabolism
enzymes to osteoporosis
Improvement of transdermal permeation of captopril by iontophoresis
Nonlinear pharmacokinetics of paclitaxel in ovarian cancer patients
Effects of corticotrophin on pain behavior and BDNF, CRF levels in frontal
cortex of rats suffering from chronic pain
Effect of dizocilpine maleate on discriminative properties of methamphetamine
in rats
Estradiol potentiates antiarrhythmic and antioxidative effects of intermittent
hypoxic rat heart
IntracarOtid infusion Of hyPertOnic mannitol changes perneability Of blood-brain
barrier tO methotrexate in rats
NMDA receptor mechanism involved in arterial baroreflex
Effects of MN-9202 on platelet aggregation, 5-HT release, TXB2 synthesis,
and calcium mobilization in rabbit platelets in vitro
Regulation of α1-adrenoceptor on rat hepatocyte apoptosis induced by D-galactosamine
and lipopolysaccharide
Antioxidant activity of polyphenols from seeds of Vitis amurensis in vitro
Probucol inhibits lipid peroxidation of macrophage and affects its secretory
properties
Thrombin stimulates MMP-9 mRNA expression through AP-1 pathway in human
mesangial cells
Effects of antisense IRAK-2 oligonucleotides on PGI, release induced by
IL-1 and TNF
Induction of platelet activation by cobra venom factor from Naja naja
atra in rat
Apoptosis induced by 5-flucytosine in human pancreatic cancer cells genetically
modified to express cytosine deaminase
Pharmacokinetics of perlolyrine in rats by stable isotope dilution in
conjunction with GC-MS
l-Stepholidine facilitates inhibition of mPFC DA receptors on subcortical
NAc DA release
Effects of glutamine on tumor growth and apoptosis of hepatoma cells
No.8
1. Review
Polymorphism of CYP450 and cancer susceptibility
2.Original Research
Gender difference in letrozole pharmacokinetics in rats
Interaction of combined administration of intrathecal morphine with subcutaneous
morphine or buprenorphine
Enzyme kinetics and inhibition of nimodipine metabolism in human liver
microsomes
Mechanisms of regulation of tyrosine phosphorylation of NMDA receptor
subunit 2B after cerebral ischemia/reperfusion
Building 3D-structural model of kappa opioid receptor and studying its
interaction mechanism with dynorphin A(1-8)
Inhibition of calcium signaling in terminal and soma of carp retinal bipolar
cells by GABA
Changes and mechanisms of protein-tyrosine kinase and proteintyrosine
phosphatase activities after brain ischemia/reperfusion
Effects of salvianolic acid-A on rat hepatic stellate cell proliferation
and collagen production in culture
Antihypertensive effects of D-polymannuronic sulfate and its related mechanisms
in renovascular hypertensive rats
Rapid assay of A1c-type glycosylated hemoglobin in blood of diabetic rats
using fast protein liquid chromatography
Inhibitory effect of disodium quercetin-7, 4＇-disulfate on aggregation
of pig platelets induced by thrombin and its mechanism
Human hepatoma cell telomerase activity inhibition and cell cycle modulation
by its RNA component antisense oligodeoxyribonucleotides
In vitro proguanil activation to cycloguanil is mediated by CYP2C19and
CYP3A4 in adult Chinese liver microsomes
Probing CYP2C19 and CYP3A4 activities in Chinese liver microsomes by quantification
of 5-hydroxyomeprazole and omeprazole suiphone
Regulation of telomerase activity in camptothecin-induced apoptosis of
human leukemia HL-60 cells
Immunosuppressive effects of rubidatum in mice
7th National Congress on Anti-inflammation and Immunopharmacology
5th Annual Meeting of Shanghai Society for Pharmacology and Toxicology
2nd National Symposium on Medicinal Herbs and Chinese Traditional Medicine
Products Development
7th International Symposium on Resistance Arteries
3rd International Conference on Transgenic Animals (3rd ICTA)( with biotech
exhibition)
Papers are welcome
Free BioWhittaker Technical Seminars on Limulus Amebocyte Lysate (LAL)
and Cell
2000 International Symposium on Signal Transduction ( 2ooo ISST)-Protein
Modules and Signaling Networks(with biotech exhibition)
No.9
Inducible overexpression of Bak sensitizes HCC-9204 cells to apoptosis
induced by doxorubicin
Inhibition of experimental cirrhosis in rats by HD-03
Triptolide: a potent inhibitor of NF-kB in T-lymphocytes
Effect of protein kinase C on guinea pig sperm acrosome reaction induced
by progesterone
Metabolism of ginsenoside by intestinal bacteria Ⅱ.Immunological activity
of ginsenoside and Rh1
Effects of rhM-CSF expressed in silkworm on cytokine productionsand membrane
molecule expressions of human monocytes
Influence of AVP4-8 on MAPK activity in astrocytic glial and fetalneuronal
cells in primary culture
Adenovirus-mediated expression of human secretor type a(1,2)fucosyltransferase
reduces level of Gala(1,3)Gal epitop
Facilitating effects of histamine on spatial memory deficit inducedby
scopolamine in rats
Alterations of amino acid levels from striatum, hippocampus, andcerebral
cortex induced by global cerebral ischemia in gerbil
Effects of MCI-154, a calcium sensitizer, on cardiac function inendotoxemic
rabbits
Effect of MCI-154, a calcium sensitizer, on calcium sensitivity of myocardial
contractile system in endotoxemic rats
Inhibitory effects of purified green tea epicatechins on contractionand
proliferation of arterial smooth muscle cells
Effect of melittin on potassium currents and action potential in ventricular
myocytes of guinea pig
Hypoxic preconditioning upregulates KATP channels through activation of
protein kinase C in rat ventricular myocytes
Effect of valsartan and fosinopril on catecholamine-induced cardiac hypertrophy
Free radical scavenging and inhibition of lipid peroxidation by magnesium
lithospermate B
Effects of magnesium lithospermate B on aggregation and 5-HT release in
rabbit washed platelets
Asian-Pacific Conference of Tumor Biology2001 & 5th National Symposium
on Tmnor Mark
XXXIV International Congress of Physiological Sciences
6th National Congress on Chemotherapeutic Pharmacology
5th World Congress on Inflammation
No.10
1. Review
Calcitonin gene-related peptide: an endogenous mediator of preconditioning
2. Original Research
Prostaglandins but not nitric oxide are endothelium-derived relaxing factors
in the trout aorta
Effects of microiontophoretically-applied opioid peptides on Purkinje
cells in the cat cerebellum
Relevance between striatal expression of Fos, proenkephalin mRNA, prodynorphin
mRNA and rotation induced by l-stepholi dine in 6-hydroxydopamine-lesioned
rats
Moclobemide-induced gynecomastia in rats
Dithiolane analogs of lignans inhibit interferon-γ and lipopolysaccharide-induced
nitric oxide production in macrophages
Effect of histamine Ha-receptor antagonist clobenpropit on spatial memory
of radial maze performance in rats
Synaptic interaction between GABAergic terminals and substance P receptor-positive
neurons in rat spinal superficial laminae
Effect of ginsenoside on IL-1β and IL-6 mRNA expression in hippocampal
neurons in chronic inflammation model of aged rats
Tripterygium wilfordii saponins and interleukin-1O prevent induc tion
of experimental autoimmune thyroiditis by dendritic cells
Influence of tramadol on morphine discriminative behavior in rats
Effects of diltiazem on down-regulation of lymphocyte β-adrenoceptors
in patients with chronic congestive heart failure1
Inhibition by agmatine on spontaneous activity of rabbit atrioventricular
node cells
1-Methyl-з-isobutylxanthine delays apoptosis induced by deprivation of
growth factors in vascular endothelial cells
Antiangiogenic effect of alpha-anordrin in vitro and in vivo
Nociceptin inhibits electric field stimulation-induced cholinergic constrictions
in rat airways
In vitro inhibition of rat monoamine oxidase by liquiritigenin and isoliquiritigenin
isolated from Sinofranchetia chinensis
Population pharmacokinetic analysis of amikacin and validation on neonates
using Monte Carlo method
Subscriptions are welcome For International Subscriptions please contact
Fourth International Congress on Peer Review in Biomedical Publication
International Conference on Pathophysiology and Drug Therapy of Cardiovascular
Disorders
Couuld you find our journal information on the Web ?
7th International Symposiun on Resistance Arteries
No.11
Benznidazole-induced ultrastructural and biochemical alterations in rat
colon
Effect of selective IL-6 inhibitor Am-80 on experimental autoimmune encephalomyelitis
in DA rats
Extracellular detection of delayed afterdepolarization of cardiac fibers
using signal averaging technique
Swelling-activated chloride currents in embryonic chick heart cells
Effects of p38 and p42/p44 CCDPK signaling on H2O2-induced apoptosis in
bovine aortic endothelial cells
FUT2 gene involved in expression of H blood group antigen on surface of
human tumor cell lines BEL-7404, SGC-7901, and SPC-A-1
Sympathectomy induces novel purinergic sensitivity in sciatic afferents
Adenovirus-mediated expression of antisense RNA transcripts complementary
to pig a(1,3) galactosyltransferase mRNA inhibits expression of Gal α(1,3)
Gal epitope
Influence of idazoxan on analgesia, tolerance, and physical dependence
of morphine in mice and rats in vivo
Blocking effect of tricyclopinate on nicotinic receptors in cultured sympathetic
neurons
High-throughput screening for human collagenase 1 inhibitors
Determination of fluoxetine and its metabolite norfiuoxetine in human
liver microsomes by reversed-phase HPLC in vitro
G-2964A and C734A genetic polymorphisms of CYP1A2 in Chinese population
Effects of angiotensin Ⅱ on release of CRH and AVP from hypothalamus during
acute hypoxia
Plasma CPU-86017 concentrations regarding suppression of ouabain-induced
cardiac arrhythmias and decrease of heart rate in guinea pigs
Effect of combination of valsartan with benazepril on blood pressure and
left ventricular hypertrophy in SHR
Proceedings of The 11th China and Japan Joint Meeting on Pharmacology
(CJP- 2000) and The 7th International Symposium on Biopeptides Medical
Sciences ( BMS - 2000)
International Symposium on Cardiovascular Remodeling, Ion channelpathy,
Arrhythnnias and Drug Treatment
3rd National Conference of Chinese Society of Toxicology
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