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Acta Pharmacologica Sinica
中国药理学报(In English) Vol.22-2001
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No.1
Role of calcitonin gene-related peptide in prostaglandins-mediated ischemic
preconditioning in guinea pig hearts
Stimulation by melittin of Na+ -Ca2+ exchange current in ventricular myocytes
of guinea pigs
Inhibitory effect of recombinant TGFα-PE40 on neointimal proliferation
after arterial balloon injury
Uridine triphosphate prolongs action potential duration of guinea pig
papillary muscles via P2Y2 purinoceptors
Effect of cathepsin B on thymocyte apoptosis in spontaneously hypertensive
rats
Frequency dependent prolongation of effective refractory period by a complex
class Ⅲ antiarrhythmic agent CPU-86017
Cholinesterase inhibition by aluminium phosphide poisoning in rats and
effects of atropine and pralidoxime chloride
Inhibitory effect of nomegestrol acetate on steroidogenesis of cultured
granulosa cells from rat ovary in vitro
Development of quantitative structure-activity relationships in toxicity
prediction of complex mixtures
A 3D-structural model of memapsin 2 protease generated from theoretical
study
Uptake of cyclosporine A loaded colloidal drug carriers by mouse peritoneal
macrophages in vitro
Effects of calcitriol and its analogues on interaction of MCP-1 and monocyte-derived
dendritic cells in vitro
Gene expression of monocyte chemoattractant protein-1 in human monocytes
by exposure to advanced glycosylation end products
Prognostic value of dobutamine stress test in patients with septic shock
Relationship of symptomatology, gender, and antipsychotic drug treatment
with plasma homovanillic acid in schizophrenia1
Effects of AP-V and bicuculline on somatostatin-positive neurons in hypothalamus
of rats subjected to acute hypobaric hypoxia1
Effects of CYP2C19 genotype and CYP2C9 on fluoxetine N-demethylation in
human liver microsomes
Pharmacokinetics of enantiomers of trans-tramadol and its active metabolite,
trans-O-demethyltramadol, in human subjects
Corrigendum
11th European Congress of Clinical Microbiology and Infectious Diseases
International Symposium on Environmental Genome and Pharmacogenetics
No.2
Effect of ketamine on presympathetic neurons in rostral ventrolateral
medulla of rats
Gating kinetics of potassium channel and effects of nerve growth factors
in PC12 cells analyzed with fractal model
P-glycoprotein regulated transport of glutamate at blood-brain barrier
VEGF induced hyperpermeability in bovine aortic endothelial cell and inhibitory
effect of salvianolic acid B
Effect of copper aspirinate on contraction of isolated rabbit aortic strips
Inhibitory effects of berberine on IK1, IK, and HERG channels of cardiac
myocytes
Allitridum mimics effect of ischemic preconditioning by activation of
protein kinase C
Blood pressure variability is increased in genetic hypertension and L
-NAME-induced hypertension
Involvement of calcitonin gene-related peptide in nitroglycerin induced
improvement of preservation with cardioplegic solution
Role of cytochrome P450 in estradiol metabolism in vitro
Effects of droloxifene on apoptosis and Bax, Bcl-2 protein expression
of luteal cells in pseudopregnant rats
Endogenous production of protoporphyrin IX induced by 5-aminolevulinic
acid in leukemia cells
Glucose transporter in human glomerular mesangial cells modulated by transforming
growth factor-beta and rhein
Cycloheximide blocks TGF-β1-induced apoptosis in murine hepatocytes
Antifibrotic effects of matrine on in vitro and in vivo models of liver
fibrosis in rats
Evaluate multiple adverse events in crossover design bioequivalence clinical
trials
No.3
1. Review
Carvedilol and vesnarinone: new antiarrhythmic approach in heart failure
therapy
Endoxin: a major factor regulating cardiovascular system
2.Original Research
Accumulation of ofloxacin and tosufloxacin in fluoroquinolone-resistant
E coli
Effect of change in oxygen tension on release pattern and nature of endothelium-derived
substances in isolated rabbit aorta
Anxiolytic effect of BPC-157, a gastric pentadecapeptide: shock probe/burying
test and light/dark test
Human xenoreactivity is reduced in mice bearing porcine antisenseα(1,3)
galactosyltransferase cDNA
Cimetidine inhibits production of interferon γ and tumor necrosis factor
α by splenocytes in aplastic anemic mice
Effect of dopamine depletion on DARPP-32 protein in ischemic rat striatum
A phospholipase C inhibitor, phenylmethylsulfonyl fluoride,ameliorates
ischemic injury to brain mitochondria in rats
Puerarin blocks transient ourward K + current and delayed rectifier K+
current in mice hippocampal CA1 neurons
Inhibition of cultured rat prostatic epithelial cell growth by epristeride
in vitro
Agmatine inhibits carotid sinus baroreflex in anesthetized rats
5-HT1B receptor augmented 5-HT vasoconstrictor response of pulmonary artery
in monocrotaline-induced pulmonary hypertensive rats
Hypercholesterolemia alters vascular functions and gene expression of
potassium channels in rat aortic smooth muscle cells
Inhibitory effect of melittin on Na+, K+-ATPase from guinea pig myocardial
mitochondria
Interindividual variations in levels and activities of cytochrome P-450
in liver microsomes of Chinese subjects
No.5
1. Review
Advantages of pyruvate over lactate in peritoneal dialysis solutions
2.Original Research
Effects of hepatocyte growth-promoting factor and panax notoginseng saponins
on intrasplenic hepatocellular autotransplantation
Atrophy and apoptosis in ventral prostate of rats induced by 5a-reductase
inhibitor, epristeride
Opposing effect of p38 CCDPK and p44/42 CCDPK signaling on TNF-α-induced
apoptosis in bovine aortic endothelial cells
Effects of erysimin G on renal tubular function and 70-pS K+ channel activity
of thick ascending limb
DDPH inhibited L-type calcium current and sodium current in a single ventricular
myocyte of guinea pig
Thrombolysis effect with F Ⅱ a from Agkistrodon acutus venom in different
thrombosis model
Protective effect of nimodipine against cerebral injury induced by subacute
carbon monoxide intoxication in mice
Preventive effects of ginsenosides on osteopenia of rats induced by ovariectomy
Effect of sodium dimercaptopropanesulfonate on antagonism of tetramethylenedisulphotetramine
to GABA receptor
17β-Estradiol inhibits carotid sinus baroreceptor activity in anesthetized
male rats
Contractile responses of diabetic rat aorta to phenylephrine at different
stages of diabetic duration1
Pharmacokinetics of lactosaminated recombinant human growth hormone in
mice
Effect of insulin on oxygen free radicals and oxidative phosphorylation
in liver mitochondria of diabetic rats
Inhibition of serum deprivation-induced PC12 cell apoptosis by tanshinone
Ⅱ A
Structure-activity relationship of tubeimosides in anti-inflamma-tory,
antitmnor, and antitumor-promoting effects
Demethylation metabolism of roxithromycin in humans and rats
Effect of theophylline on airway inflammation in asthma
No.6
Responses to adenosine of isolated transverse or spiral strips of sensitized
guinea pig trachea: role of epithelium
Effect of centrally administered oxytocin on gastric and duodenal ulcers
in rats
Identification of Atractylodes plants in Chinese herbs and formulations
by random amplified polymorphic DNA
Evidence against inhibition of sarcoplasmic reticulum Ca2+ -pump as mechanism
of H2O2-induced contraction of rat aorta
NO mediated increase of Fos protein and NMDA1A R mRNA expression in rat
spinal cord during morphine withdrawal
Effects of matrine, artemisinin, and tetrandrine on cytosolic [ Ca2+ ]i
in guinea pig ventricular myocytes
Effect of epristeride on expression of TGF-β receptor in rat prostatic
epithelial cells in vitro
Pharmacological study on recombinant human GABA-A receptor complex containing
α5 (leucine155 to valine) combined with β3γ2s subunits
Mifepristone regulates expression of apoptosis related genes Fas and FasL
in mouse endometrium
Naltrexone microspheres: in vitro release and effect on morphine analgesia
in mice
Effects of dexamethasone on Flt3 receptor expression and proliferation
induced by recombinant human F1t3 ligand in malignant hematopoietic cells
Additional effects of endothelin receptor blockade and angiotensin converting
enzyme inhibition in rats with chronic heart failure
PEGylated recombinant human tumor necrosis factor alpha: preparation and
anti-tumor potency
Neurotoxic effect of high dose of L-( + )-2-amino-3-phosphono propionic
acid in rats after intracaudatal injection
Inhibition by nociceptin on excitatory non-adrenergic non-cholinergic
response in guinea pig airways
Increment of calcium-activated and delayed rectifier potassium current
by hyposmotic swelling in gastric antral circular myocytes of guinea pig
Pharmacokinetics of anastrozole in Chinese male volunteers
No.7
1. Review
Neuroimmunologic influences in neuropsychiatric and psychophysiologic
disorders
2. Original Research
Effects of calcitonin gene-related peptide and BIBN4096BS on myocardial
ischemia in anesthetized rats
Elcatonin-mediated contractile and relaxant responses in SHR femoral artery
Effects of cysteamine on nociception in mice
Effect of H1-antagonists on spatial memory deficit evaluated by 8-arm
radial maze in rats
Porphyromonas gingivalis lipopolysaccharide activated bone resorption
of osteoclasts by inducing IL-1, TNF, and PGE
A novel human tumor necrosis factor mutant showed potent antitumor activity
and reduced toxicity in vivo
Gene construction, expression, and characterization of double-copy truncated
form of human insulin-like growth factor Ⅰ
Salvianolate inhibits proliferation and endothelin release in cultured
rat mesangial cells
Single plasma sampling to predict oral clearance of CYP3A probe midazolam
Down-regulation of MAO-B activity and imidazoline receptors in rat brain
following chronic treatment of morphine
PEGylated polycyanoacrylate nanoparticles as salvicine carriers:synthesis,
preparation, and in vitro characterization
Triptolide inhibits vascular endothelial growth factor expression and
production in endothelial cells
Effects of ginsenoside on synaptic plasticity of freely moving rats and
its mechanism of action
Predicting blood-brain barrier penetration of drugs by polar molecular
surface area and molecular volume
Inhibitory role of GDP on saikosaponin (Ⅰ) stimulated enzymes secretion
and rising of [ Ca2＋]i in rat pancreatic acini
No.8
Protective effect of ginsenoside Rg1 on dopamine-induced apoptosis in
PC12 cells
Effects and mechanisms of triacetylshikimic acid on platelet adhesion
to neutrophils induced by thrombin and reperfusion after focal cerebral
ischemia in rats
Activation of p42/44 mitogen-activated protein kinase pathway in long-term
potentiation induced by nicotine in hippocampal CA1 region in rats
Quantitative design of optimal analgesic combination of acetaminophen,
caffeine, and butalbita
Effects of melittin on isolated papillary muscles of guinea pig
Effect of dipfluzine on L-type calcium current in guinea pig ventricular
myocytes
Antiproliferative effects of D-polymannuronic sulfate on rat vascular
smooth muscle cells and its related mechanisms
Inhibitory effect of aminoguanidine on bleomycin-induced pulmonary toxicity
in rat
Cladonia furcata polysaccharide induced apoptosis in human leukemia K562
cells
Effects of Tripterygium wilfordii saponins and interleukin-10 on dendritic
cells from human peripheral blood
Down-regulation of four arsenic antagonists on apoptosis and telomerase
activity induced by arsenic trioxide in three myelocytic leukemia cell
lines
Multiple drug resistance phenotype of human endothelial cells induced
by vascular endothelial growth factor 165
Roles of IL-4 and other factors in trichosanthin-induced ovalbumin-specific
IgE response
DNA topoisomerase Ⅱ as primary cellular target for salvicine in Saccharomyces
cerevisiae
Distribution of angiotensin converting enzyme gene polymorphism among
Northern Hans, Daurs, and Ewenkis
Cloning of a novel mouse Gabarapl2 cDNA and its characterization
Effects of L-arginine on proliferation of human renal mesangial cells
and production of extracellular matrix
Delivery of glucocorticoid conjugate in rat gastrointestinal tract and
its treatment for ulcerative colitis
Matrine inhibits production and actions of fibrogenic cytokines released
by mouse peritoneal macrophages
Correction
No.9
Effects of 12 beticolins, Cercospora beticola toxins, on proliferation
of ras-transformed adrenocortical cell
Propranolol increases phosphatidic acid level via activation of phospholipase
D
Effect of diethyldithiocarbamate on proliferation,redifferentiation, and
apoptosis of human hepatoma cells
Effect of genistein and quercetin on proliferation, collagensynthesis,
and type Ⅰ procollagen mRNA levels of rat hepaticstellate cells1
Improvement of melatonin on learning and memory impairmentinduced by amyloid
β-peptide 25- 35 in elder rats
Postantibiotic effects of eleven antimicrobials on five bacteria
Antinociceptive effect of astragalosides and its mechanism of action
Effect of dl-praeruptorin A on ATP sensitive potassium channels inhuman
cortical neurons
Substance P potentiates thermal hyperalgesia induced by intrathecal administration
of D-serine in rats1
Development of a K562 cell-based assay for screening anticancer agents
Relationship between lactone ring forms of HCPT and their antitumor activities
Anti-human hepatocellular carcinoma effects of tumor necrosis factor-related
apoptosis-inducing ligand in vivo and in vitro1
Quaternary ammonium salt derivative of haloperidol inhibits KC1-induced
calcium increase in rat aortic smooth muscle cells
Knockdown of IGF- Ⅰ R by antisense oligodeoxynucleotide auguments sensitivity
of T24 bladder cancer cells to mitomycin
Inhibition of regrowth of prostatic glandular cells by epristeride
Role of calcitonin gene-related peptide in nitric oxide-mediated myocardial
delayed preconditioning induced by heat stress
Effect of quercetin on adhesion of platelets to microvascular endothelial
cells in vitro1
High concentration of glucose inhibits endothelium-dependent vasorelaxation
of rabbit aortic artery
No.10
Fluoxetine inhibits dendrite atrophy of hippocampal neurons by decreasing
nitric oxide synthase expression in rat depression model
Distribution of enantiomers of trans-tramadol and trans-O-demethyltramadol
in central nervous system of rats
Effects of recombinant human basic fibroblast growth factor on restenosis
after arterial endothelial injury in rats
Naloxone increases vascular responsiveness in chronic morphine treated
rats and facilitates intracellular signaling in cultured vascular cells
Signaling pathway mediated by κ-opioid receptor is impaired in cardiac
hypertrophy
Effects of endothelin receptor A antagonist FR139317 on rats with congestive
heart failure
Killing effects of ganciclovir on human pulmonary adenocarcinoma cell
A549 transduced with HSV1-TK gene in vitro and in vivo
Sympathetic cotransmission in rabbit saphenous artery in vitro:effect
of electric stimulation and potentiation by α, β-methylene ATP
Effects of methylprednisolone and aprotinin on phospholipase D activity
of leukocytes in systemic inflammatory response induced by cardiopulmonary
bypass
Verapamil, cyproheptadine, and anisodamine antagonized [ Ca2 + ] ielevation
induced by TNFα in a single endothelial cell
Expression of 5-HT2A receptor mRNA in rat nucleus raphe magnus neurons
after peripheral inflammation
Effect of scopoletin on PC3 cell proliferation and apoptosis
Rhein inhibits renal tubular epithelial cell hypertrophy andextracellular
matrix accumulation induced by transforming growth factor
B9-serine residue is crucial for insulin actions in glucose metabolism
Stereoselective metabolism of propafenone by human liver CYP3A4expressed
in transgenic Chinese hamster CHL cells lines
Genetic modification of hematopoietic progenitor cells for combined resistance
to 4-hydroperoxycyclophosphamide, vincristine, and daunorubicin
Simultaneous modeling of pharmacokinetics and pharmacodynamics of propafenone
in healthy subjects
No.11
Ethacrynic acid inhibits pancreatic exocrine secretion
Stimulation of dopamine receptors inhibited Ca2+-calmodulin- dependent
protein kinase Ⅱ activity in rat striatal slices
Effect of tetrandrine on neutrophilic recruitment response to brain ischemia/reperfusion
Analgesic effect of endomorphin-1
Analysis of binding domain and function of chimeric opioid receptors to
ohmefentanyl stereoisomers1
Inhibitory effect of jujuboside A on penicillin sodium induced hyperactivity
in rat hippocampal CA1 area in vitro1
Correlation between decrease of 11β-hydroxysteroid dehydrogenase activity
and hypokalemia induced by furosemide in rats
Effects of microinjection of melatonin and its receptor antagonists into
anterior hypothalamic area on blood pressure and heart rate in rats
Regulation of growth-regulated oncogene expression by estrogen in human
endothelial cells
Cationic lipids enhanced cellular uptake and activity of bcl-2 antisence
oligodeoxynucleotide G3139 in HL-60 cells
Subcellular expression of UGT1A6 and CYP1A1 responsible for propofol metabolism
in human brain
Erianin induces apoptosis in human leukemia HL-60 cells
Reversal effects of droloxifene on multidrug resistance in adriamycin-resistant
K562 cell line
Role of Fas/FasL genes in azoospermia or oligozoospermia induced by testosterone
undecanoate in rhesus monkey
Mechanism of FK506-induced renal hypoperfusion and its reversion in rats
Dual function of human tumor necrosis factor receptor 75 in cytotoxicity
induced by human tumor necrosis factor α
Lowering of sodium deoxycholate-induced nasal ciliotoxicity with cyclodextrins
Nasal absorption enhancement of insulin by sodium deoxycholate in combination
with cyclodextrins
No.12
Constituents and pharmacological effects of Eucommia and Siberian ginseng
Current studies on anti-endotoxic chemical components of traditional Chinese
medicine in China
Original Research
Improving effects of SSF on memory deficits and pathological changes of
neural and immunological systems in senescent mice
Antistress effect of oligosaccharides extracted from Morinda officinalis
in mice and rats
Protective effect and mechanism of Ginkgo biloba leaf extracts for Parkinson
disease induced by 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine
Antioxidant properties of phenolic diterpenes from Rosmarinus officinalis
NO mediates ginsenoside Rg1-induced long-term potentiation in anesthetized
rats
Inhibitory effect of quercetin on cultured neonatal rat cardiomyocytes
hypertrophy induced by angiotensin Ⅱ
Effect of sea anemone toxin anthopleurin-Q on sodium current in guinea
pig ventricular myocytes
Wound healing activity of human placental extracts in rats
Anti-inflammatory effect and mechanism of proanthocyanidins from grape
seeds
Chemo-and radio-protective effects of polysaccharide of Spirulina platensis
on hemopoietic system of mice and dogs
Effect of Salvia miltiorrhiza Bunge injectio on anticardiolipin antibody
production induced by β2 glycoprotein Ⅰ
Effect of phenolic alkaloids from Menispermum dauricum on myocardial-cerebral
ischemia-reperfusion injury in rabbits
Magnesium lithospermate B inhibits hypoxia-induced calcium influx and
nitric oxide release in endothelial cells
Effect of Rhizoma Corydalis on focal cerebral infarct in ischemia reperfusion
injured rats
Danggui Shaoyao San improve colchicine-induced learning acquisition impairment
in rats
Effects of Huangqi Jianzhong Tang on hematological and biochemical parameters
in judo athletes
Prophylactic effect of four prescriptions of traditional Chinese medicine
on α-naphthylisothiocyanate and carbon tetrachloride induced toxicity
in rats
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