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Acta Pharmacologica Sinica
ÖйúÒ©Àíѧ±¨£¨In English£©Vol.23-2002
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No.1

Viral and immunologic follow up of 4 to 9 years of AIDS treatments by quadruple combinations of virostatics including integrase inhibitors applied in short sequences differing by drug rotation¡¡

Mechanism of growth hormone insensitivity induced by endotoxin¡¡ ¡¡

Opioid mediated anti-nociceptive effect of domperidone and cisapride in mice¡¡ ¡¡

Assessing physiological concentrations of endogenous substances in situ by inducing calcium oscillations in vitro. Case of liver¡¡ ¡¡¡¡

Involvement of heme oxygenase-1 in delayed cardioprotection induced by monophosphoryl lipid A in rats¡¡ ¡¡¡¡

Endomorphins inhibit contractile responses of rat thoracic aorta rings induced by phenylephrine and angiotensin ¢ò in vitro¡¡ ¡¡

VEGF protects bovine aortic endothelial cells from TNF-¦Á- and H2O2-induced apoptosis via co-modulatory effects on p38- and p42/p44-CCDPK signaling¡¡ ¡¡¡¡

Effects of ropivacaine on sodium, calcium, and potassium currents in guinea pig ventricular myocytes¡¡ ¡¡

Adeno-associated virus mediated expression of human erythropoietin in vitro¡¡ ¡¡¡¡

Norepinephrine metabolism in neuron: dissociation between 3, 4-dihydroxyphenylglycol and 3,4-dihydroxymandelic acid pathways¡¡ ¡¡

Effects of brain histamine on memory deficit induced by nucleus basalis-lesion in rats¡¡ ¡¡

Protective effects of melatonin on cortico-hippocampal neurotoxicity induced by amyloid beta-peptide 25-35¡¡ ¡¡

Identification of three sulfate-conjugated metabolites of berberine chloride in healthy volunteers' urine after oral administration¡¡ ¡¡¡¡

Stereoselectivity in renal clearance of trans-tramadol and its active metabolite, trans-O- demethyltramadol¡¡ ¡¡

Restricted-access media high pressure liquid chromatography vs fluorescence polarization immunoassay for analysis of carbamazepine in human plasma¡¡

Inhibition of ll¦Â-hydroxysteroid dehydrogenase in guinea pig kidney by three bioflavonoids and their interactions with gossypol¡¡ ¡¡

Information for authors¡¡¡¡(¢ñ)
Regulations of Acta Pharmacologica sinica¡¡(¢ñ)
Announcement¡¡¡¡

No.2

Direct assessment and diminished production of morphine stimulated NO by diabetic endothelium from saphenous vein¡¡

Determination of arterial baroreflex-blood pressure control in conscious rats¡¡

Characterization of transient outward K+ current and ultra-rapid delayed rectifier K+ current in isolated human atrial myocytes from patients with congestive heart failure¡¡ ¡¡

A new model for random screening inhibitors of vascular endothelial growth factor receptor 1 kinase¡¡ ¡¡

Effects of simvastatin on activities of endogenous antioxidant enzymes and angiotensin-converting enzyme in rat myocardium with pressure-overload cardiac hypertrophy¡¡ ¡¡

Inhibitory effects of praeruptorin C on cattle aortic smooth muscle cell proliferation¡¡ ¡¡

Comparison of norepinephrine-dobutamine to dopamine alone for splanchnic perfusion in sheep with septic shock¡¡ ¡¡¡¡

Inhibitory effect and mechanism of action of sanggenon C on human polymorphonuclear leukocyte adhesion to human synovial cells¡¡

Expression and purification of catalytic domain of human macrophage elastase for high-throughput inhibitor screening¡¡ ¡¡

Acetamide-45 inhibits histamine- and methacholine-induced contraction of isolated guinea pig trachea¡¡ ¡¡¡¡

VCAM-1 expression,eosinophil infiltration,and pharmacological modulation in rat allergic airway inflammation¡¡ ¡¡

Structural characterization and biological activities of SC4,an acidic polysaccharide from Salvia chinensis¡¡ ¡¡

Synergism between heparin and adriamycin on cell proliferation and apoptosis in human nasopharyngeal carcinoma CNE2 cells¡¡ ¡¡¡¡

Isolation of acetylcholinesterase G4 and G1 molecular isoforms from rat cortex¡¡

Effect of mifepristone on uterine receptivity in guinea pigs¡¡ ¡¡¡¡

Alzheimer- like tau phosphorylation induced by wortmannin in vivo and its attenuation by melatonin¡¡ ¡¡

Nonassociation of aryl hydrocarbon receptor genotypes with susceptibility to bladder cancer in Shanghai population¡¡ ¡¡

Announcement¡¡(123,151)

No.3

1. Review

Potential food contaminants and associated health risks¡¡ ¡¡¡¡

2.Original Research

Kininase-independent potentiation of endothelium-dependentrelaxations to kinins by converting enzyme inhibitor perindoprilat¡¡ ¡¡¡¡

Molecular simulation of interaction between estrogen receptor andselective estrogen receptor modulators¡¡

Estrogen prevents bovine aortic endothelial cells from TNF-¦Á-induced apoptosis via opposing effects on p38 and p44/42 CCDPK¡¡ ¡¡¡¡

Effect of agmatine on L-type calcium current in rat ventricularmyocytes¡¡ ¡¡

Cyclosporin A enhanced protection of nimodipine against braindamage induced by hypoxia-ischemia in mice and rats¡¡ ¡¡

Effects of various muscarinic ligands on M2AChR-Gi1¦Á fusion proteinexpressed in Sf9 insect cells¡¡ ¡¡¡¡

Modulation of neuronal nicotinic acetylcholine receptorsby glucocorticoids¡¡ ¡¡¡¡

Effects of cyclosporin A by aerosol on airway hyperresponsivenessand inflammation in guinea pigs¡¡ ¡¡¡¡

Correlative changes of interferon-¦Ã and interleukin-4 betweencortical layer and pulmonary airway of sensitized rats¡¡ ¡¡

Effects of lidamycin on genomic DNA in human heptatomaBEL-7402 cells¡¡ ¡¡¡¡

Effects of reactive oxygen species on lymphokine-activatedkiller cells in patients with bladder cancer.¡¡ ¡¡¡¡

Institutes for Biological Sciences, Chinese Academy of Sciences,Shanghai 200031¡¡

Effects of theophylline on CD4+T lymphocyte, interleukin-5, andinterferon gamma in induced sputum of asthmatic subjects¡¡

Inhibition of ¦Â-estradiol on trachea smooth muscle contractionin vitro and in vivo¡¡ ¡¡

Pharmacodynamics and pharmacokinetics of inhaled nitric oxide indogs with septic acute respiratory distress syndrome1¡¡ ¡¡

Determination of domperidone in human plasma by LC-MS and itspharmacokinetics in healthy Chinese volunteers¡¡ ¡¡

Announcement¡¡ ¡¡¡¡¡¡

No.4

Effect of tachykinins on ascending and descending reflex pathway in rat small intestine¡¡ ¡¡¡¡

Effect of diet supplementation with l-carnitine on hepatic catabolism of l-alanine in rats¡¡ ¡¡

Effect of phorbol esters on activity of Ha-ras gene promoter in HeLa cells¡¡ ¡¡¡¡

Myocardial capillary angiogenesis and coronary flow in ischemia tolerance rat by adaptation to intermittent high altitude hypoxial¡¡ ¡¡¡¡

Desipramine antagonized corticosterone-induced apoptosis in cultured PC12 cells¡¡

Apoptotic effects of ginsenoside Rh2 on human malignant melanoma A375-S2 cells¡¡

Effect of safrole oxide on vascular endothelial cell growth and apoptosis induced by deprivation of fibroblast growth factor¡¡ ¡¡¡¡

Expression of intercellular adhesion molecule-1 in U937 foam cells and inhibitory effect of imperatorin¡¡ ¡¡¡¡

Inhibitory effects of prostaglandin A1 on apoptosis of rat cardiac microvascular endothelial cells was mediated by NF-¦ÊB¡¡ ¡¡

Reduction in monocyte chemoattractant protein-1 mRNA expression in peripheral blood mononuclear cells of diamorphine addicts¡¡ ¡¡

Effect of semi-synthesized quercetin water-soluble derivatives on recombinant human phosphatidylinositol 3-kinase p110¦Â catalytic subunit¡¡ ¡¡¡¡

Immunomodulatory activity of orphanin FQ/nociceptin on traumatic rats¡¡ ¡¡¡¡

Localization of CCT¦Â in rat brain and overexpression in insect cells¡¡ ¡¡¡¡

Reversal of scopolamine-induced spatial memory deficits in rats by TAK-147¡¡ ¡¡¡¡

Effects of histidine, a precursor of histamine, on pentylenetetrazole-induced seizures in rats¡¡ ¡¡¡¡

Electrophysiological effects of phytoestrogen genistein on pacemaker cells in sinoatrial nodes of rabbits¡¡ ¡¡¡¡

Dauricine-induced changes in monophasic action potentials and effective refractory period of rabbit left ventricle in situ¡¡ ¡¡¡¡

Influence of piperacillin on pharmacokinetics of etimicin in healthy volunteers¡¡

Pharmacokinetics of multiple intravenous instillation of levofioxacin in Chinese healthy subjects¡¡ ¡¡¡¡

Announcement¡¡ ¡¡¡¡

No.5

1. Review

Effects of stereochemical aspects on drug interaction in pharmacokinetics¡¡ ¡¡¡¡

2. Original Research

Beneficial effects of long-term administration of ONO-3144, a freeradical scavenger, on stroke-prone SHR¡¡ ¡¡¡¡

Trypanocidal action of 2,4- dichloro- 6- phenylphenoxyethyl diethylamine hydrobromide (Lilly 18947) on Trypanosoma cruzi¡¡ ¡¡¡¡

Expression of angiopoietin-2 and vascular endothelial growth factor in mice cerebral cortex after permanent focal cerebral ischemia¡¡ ¡¡¡¡

Pentadecapeptide BPC 157 attenuates chronic amphetamineinduced behavior disturbances¡¡ ¡¡

Interaction of multidrug resistance reversal agents with P-glycoprotein ATPase activity on blood-brain barrier¡¡ ¡¡¡¡

Interactions between quinolone antibiotics and phospholipid membrane for prediction of alveolar macrophage uptake in vitro¡¡ ¡¡¡¡

Anti- inflammatory effect of recombinant human superoxide dismutase in rats and mice and its mechanism¡¡ ¡¡¡¡

Effect of rhynchophylline on apoptosis induced by dopaminein NT2 cells¡¡ ¡¡¡¡

Cloning and characterization of a novel isoform of calpastatin in human adult testis¡¡ ¡¡

Metabolism of roxithromycin in phenobarbital-treated rat livermicrosomes¡¡ ¡¡¡¡

Caspases promoted DADAG-induced apoptosis in human leukemia HL-60 cells¡¡ ¡¡¡¡

Hypoglycemic efficacy of pulmonary delivered insulin dry powder aerosol in rats¡¡

In vitro metabolic characteristics of cytochrome P-450 2A6 in Chinese liver microsomes¡¡ ¡¡¡¡

Effects of scopolamine and physostigmine on acquisition of morphine-treated rats in Morris water maze performance¡¡ ¡¡

Announcement¡¡ ¡¡(392¡¢398)

No.6

Comparisons of somatic action potentials from dispersed and intact rat nodose ganglia using patch-clamp technique¡¡ ¡¡¡¡

Norepinephrine-induced calcium mobilization in C6 glioma cells¡¡ ¡¡

Arachidonate CYP hydroxylases of kidney contribute to formation of hypertension and maintenance of blood pressure¡¡ ¡¡¡¡

Effects of "Chinese yam" on hepato-nephrotoxicity of acetaminophen in rats¡¡ ¡¡¡¡

Effects of recombinant staphylokinase on coronary thrombosis in Chinese experimental miniature swine¡¡ ¡¡

Probucol inhibits oxidized-low density lipoprotein-induced adhesion of monocytes to endothelial cells in vitro¡¡ ¡¡¡¡

5-Hydroxytryptamine enhances L-type calcium current in norepinephrine-induced hypertrophic ventricular myocytes¡¡ ¡¡

Inhibition of Na+/Ca2+ exchange by hexapeptide FRCRSFa in rat ventricular myocytes¡¡ ¡¡¡¡

Effect of Misgurnus anguillicaudatus polysaccharide on immune responses of splenocytes in mice¡¡ ¡¡¡¡

Effects of Coriolus versicolor polysaccharide B on monocyte chemoattractant protein 1 gene expression in rat¡¡

Function and mechanism of pyronaridine: a new inhibitor of P-glycoprotein-mediated multidrug resistance¡¡ ¡¡

Pharmacokinetics of leflunomide in Chinese healthy volunteers¡¡ ¡¡¡¡

Inhibitory effect and its kinetic analysis of tyrphostin AG1478 on recombinant human protein kinase CK2 holoenzyme¡¡ ¡¡

Cytotoxicity of flutamide and 2-hydroxyflutamide and their effects on CYP1A2 mRNA in primary rat hepatocytes¡¡ ¡¡¡¡

Genotype of CYP3AP1 associated with CYP3A activity in Chinese Han population¡¡ ¡¡

Assessment of estrogenic activity of natural compounds using improved E-screen assay¡¡ ¡¡

Announcement¡¡ ¡¡





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