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In this book Amphioxus Immunity, Anlong Xu covers a remarkable range of information about this small fish-like organism and its evolutionary context. This compilation of what is currently known about amphioxus, with a sharp focus on its immune system, is especially timely for many reasons. The recent availability of the amphioxus genomic sequence and its comparison with other metazoan genomes firmly establishes the phylogenetic position of amphioxus as the representative head of the chordates. The new phylogeny tree thus places amphioxus basal to the sister chordate lineages, tunicates and vertebrates
About the Author
Foreword
Preface
1. Amphioxus is a model for understanding the evolution of vertebrate
2. Basic knowledge of immunology
3. Immune organs and cells of amphioxus
4. Genomic and Transcriptomic view of the amphioxus immunity
5. Pattern recognition system in amphioxus
6. Transcription factors in amphioxus
7. The complement system of amphioxus
8. The oxidative burst system in amphioxus
9. Immune effectors in amphioxus
10. Lipid signaling of immune response in amphioxus
11. Apoptosis in amphioxus
12. Primitive adaptive immune system of amphioxus
13. Future research directions
Abbreviation Index
Key Words Index
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